Transparent Intelligence Publishing Transparent Intelligence Publishing

Search

Search results:
Towards Trustworthy Brain Tumor Diagnosis: An Explainable Deep Learning Framework for MRI Analysis
Among the most critical and fatal medical conditions are brain malignancies, making early identification vital for enhancing survival rates. Currently, magnetic resonance imaging (MRI) stands as the premier diagnostic tool for early detection because of its exceptional capability to capture soft tissue details. Nevertheless, relying solely on human interpretation of brain MRI scans introduces risks of oversight, which are frequently exacerbated by the fatigue and varying expertise of radiologists. To mitigate these limitations, computer-aided diagnosis (CAD) systems have taken on an increasingly vital role. Leveraging state-of-the-art computer vision methodologies like deep learning, these systems generate highly precise diagnoses from clinical imagery, thereby boosting both precision and consistency in clinical settings. This study introduces an innovative CAD architecture designed for multi-class classification of brain malignancies. The system evaluates six pre-trained deep learning networks as its foundational architecture, integrating robust data preprocessing and augmentation protocols to optimize computational throughput. To counter the opaque "black box" nature of deep learning architectures and improve interpretability, Gradient-weighted Class Activation Mapping (Grad-CAM) is integrated to illuminate the network's deductive steps when identifying anomalies in MRI data. Furthermore, an accessible, web-based Brain Tumor Detection System was constructed using the Streamlit framework, highlighting its utility for clinical environments and offering meaningful support to medical professionals. All experimental simulations were carried out using an open benchmark repository, proving that the introduced system delivers state-of-the-art diagnostic capabilities, achieving accuracy levels near 99% with the ResNet-50, Xception, and InceptionV3 architectures.
Journal of Trustworthy and Explainable Intelligent Systems
Original Research | Open access | 15 March 2024 | Article: 45

Explainable Machine Learning for Long-Term Forecasting of Patient Demand in Urgent Care Clinics
Global emergency departments and urgent care facilities regularly experience prolonged waiting periods that surpass patient expectations, primarily driven by unexpected spikes in patient volumes. The resulting delays caused by insufficient staffing during these high-demand intervals have been associated with detrimental clinical consequences. Prior investigations into predicting patient volumes have predominantly relied on traditional statistical approaches. Furthermore, these efforts have mainly focused on short-range predictions, which offer minimal utility for the long-term scheduling of medical staff. This paper contributes to a growing domain of research aimed at investigating the capacity of machine learning frameworks to produce precise patient volume projections. Utilizing a decade's worth of data from two major urgent care centers, this study constructs long-range patient flow predictions extending up to one quarter in advance by evaluating a selection of modern, high-performing algorithms. A unique aspect of this research is the integration of eXplainable Artificial Intelligence (XAI) frameworks, specifically LIME and Shapley, to conduct a comprehensive assessment of internal model dynamics that are typically obscured. These diagnostic instruments allowed us to examine how effectively the predictive frameworks adjusted to volatile demand shifts induced by COVID-19 pandemic lockdowns, while also determining the most significant predictor variables to gain deep operational insights. The empirical findings indicate that an innovative ensemble combining gradient boosting techniques with advanced univariate frameworks like Prophet yielded the most precise and dependable performance overall. On average, this methodology produced a 16%–30% improvement over the current internal forecasting techniques utilized for predicting daily patient volumes 90 days into the future.
Journal of Trustworthy and Explainable Intelligent Systems
Original Research | Open access | 15 September 2024 | Article: 53