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Foundation models have expanded the scope of artificial intelligence by supporting language generation, multimodal reasoning, knowledge-intensive assistance, decision support, and adaptable downstream applications. Their broad capabilities, however, do not establish that their outputs, explanations, internal processes, or deployment arrangements are trustworthy. This scoping review maps the research landscape concerning foundation-model trustworthiness across interpretability, explanation capabilities, hallucination, uncertainty, reliability, alignment, evaluation, and human oversight. The review uses structured search concepts, eligibility principles, evidence extraction, and dimension-based mapping to examine how peer-reviewed scholarship characterizes foundation models as general-purpose intelligent systems and how trustworthiness evidence is distributed across technical, human-centered, organizational, and governance domains. The synthesis indicates that interpretability methods can expose selected behavioral or representational features but do not independently demonstrate explanation fidelity, usefulness, or safety. Hallucination and factuality research identifies persistent risks involving fabrication, unsupported claims, weak grounding, and persuasive misinformation, while uncertainty methods remain constrained by calibration, context shift, and user-communication challenges. Alignment and post-training techniques may shape preferred behaviors but retain risks associated with proxy objectives, preference representation, and residual failure. Benchmarking, human evaluation, stress testing, and oversight provide partial evidence, yet their value depends on construct validity, domain relevance, intervention capacity, accountability, and lifecycle monitoring. The research landscape is therefore fragmented across disciplines and frequently model-centred rather than socio-technical. Key priorities include stronger foundation-model interpretability validation, consistent hallucination measurement, usable uncertainty communication, externally valid evaluation, meaningful oversight testing, multimodal analysis, and lifecycle governance. The review contributes an integrated evidence map while emphasizing that no single trustworthiness dimension certifies safety, reliability, accountability, or deployment readiness.

Foundation models are increasingly embedded in information access, content production, analysis, communication, and decision-support processes. Their broad capabilities have intensified interest in alignment, yet alignment alone cannot establish responsible use. A model may appear responsive to instructions or preferences while remaining opaque, weakly grounded, unreliable under changing conditions, overconfident, difficult to contest, or insufficiently governed. This article proposes a conceptual governance and technical safeguard framework for responsible foundation models. The framework treats foundation models as components of decision infrastructure situated within socio-technical and institutional environments rather than as isolated predictive tools. It integrates eight interdependent areas: model and alignment safeguards; explainability and interpretability; knowledge grounding and provenance; reliability, uncertainty, and hallucination containment; human control and escalation; institutional accountability; auditability and documentation; and lifecycle monitoring and governance updating. Explainability requirements are differentiated from interpretability, transparency, explanation usefulness, and human understanding, while knowledge grounding is separated from factuality, truthfulness, source quality, and provenance. Reliability is addressed through calibration, robustness assessment, boundary testing, uncertainty communication, failure containment, and continuing monitoring. Human oversight is defined through authority, competence, review capacity, escalation pathways, contestability, and recourse rather than nominal human presence. Institutional responsibility is connected to role allocation, evidence trails, documentation, review authority, and consequences. The principal contribution is an integrated framework that clarifies how technical and governance safeguards may support responsible foundation-model assessment without treating alignment, explanation, grounding, testing, oversight, or auditing as independently sufficient. The framework requires empirical validation, domain-specific evaluation, human-centred assessment, institutional governance, and residual-risk management before it can inform consequential operational decisions.