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Pixel-Level Interpretability for Explainable Medical Imaging: A Comparative Evaluation against Grad-CAM
To overcome critical constraints regarding diagnostic accuracy and model transparency in medical imaging, this paper presents a novel framework termed the Pixel-Level Interpretability (PLI) model. The investigation primarily aims to benchmark PLI against Gradient-Weighted Class Activation Mapping (Grad-CAM) to attain superior localization correctness and highly detailed explainability. Operating on a VGG19 convolutional neural network infrastructure, the methodology incorporates three open-access COVID-19 chest X-ray datasets containing over 1000 categorized images; these underwent augmentation, normalization, and resizing steps to achieve generalizability and algorithmic stability. The experimental evaluation focused on vital performance metrics: structural similarity (SSIM), mean squared error (MSE), interpretability, computational speed, and diagnostic precision. The findings indicate that PLI drastically surpasses Grad-CAM across every evaluated metric. Specifically, PLI generated fine-grained, pixel-granular heatmaps that yielded reduced MSE, superior SSIM metrics, and expedited inference rates, demonstrating an capability to reveal minute diagnostic elements without sacrificing processing speed. Conversely, the explanations produced via Grad-CAM regularly lack the detailed resolution necessary for dependable clinical integration. By incorporating fuzzy logic to refine both numeric and visual explanations, PLI delivers transparent data that corresponds with clinical logic, thereby allowing healthcare professionals to execute decisions with greater certainty. Ultimately, this research validates PLI as a dependable framework for resolving deficiencies in AI explainability and clinical adoption. By simultaneously managing the dual demands of precision and transparency, PLI advances medical AI deployment and establishes a precedent for implementation within other high-stakes environments.
Journal of Trustworthy and Explainable Intelligent Systems
Original Research | Open access | 15 September 2022 | Article: 15

Explainable CNN-Based Cavitation Detection in Axial Piston Pumps Using Grad-CAM Visualization
The reliability and safety of an entire hydraulic system are compromised by the occurrence of cavitation in axial piston pumps. Because vibration signals can indicate cavitation states within these pumps, they have been increasingly coupled with machine learning techniques for detection purposes. Nevertheless, raw vibration signals captured under actual operating conditions are frequently corrupted by noise, complicating the precise identification of cavitation within noisy environments. To address this issue, this study introduces an intelligent methodology designed to identify cavitation in axial piston pumps under high-noise conditions. Initially, a convolutional neural network (CNN) is trained utilizing spectrogram images that are converted from raw, unstructured vibration datasets across varying cavitation states. Subsequently, the gradient-weighted class activation mapping (Grad-CAM) technique is applied to highlight and visualize the class-discriminative zones within these spectrogram images. Ultimately, a novel image processing approach leveraging the Grad-CAM heatmap is introduced to automatically filter out background noise and amplify the key class features in the spectrograms. The empirical outcomes demonstrate that this strategy substantially boosts the diagnostic efficacy of the CNN framework under noisy conditions. Specifically, the accuracy of cavitation condition classification is elevated from 0.50 to 0.89 at a signal-to-noise ratio of 4 dB, and from 0.80 to 0.92 at 6 dB.
Journal of Trustworthy and Explainable Intelligent Systems
Original Research | Open access | 15 September 2024 | Article: 55

Interpreting Convolutional Neural Network Classifications of Raman Spectra: Insights from Fungal Spores and Carotenoid-Pigmented Microorganisms
A multitude of studies demonstrate that robust predictive models for identifying microorganisms can be successfully developed by combining Raman micro-spectroscopy with chemometric techniques, frequently yielding highly accurate outcomes. Progress in machine learning alongside increased software availability has simplified the process for researchers to construct predictive frameworks from intricate data arrays. Conversely, the underlying reasons for the high accuracy of these classifications remain under-investigated. This study analyzes Raman spectroscopic datasets from fungal spores and carotenoid-producing microorganisms to demonstrate that successful differentiation is frequently independent of peak positions or subtle variations in spectral band ratios caused by minor biochemical differences among the organisms. Instead, distinctive baseline variations in biochemically related microorganisms, which may be amplified by specific data preprocessing routines, play a critical role; furthermore, seemingly neutral spectral intervals can significantly influence a convolutional neural network. By applying a technique known as Gradient-weighted Class Activation Mapping, we investigate the internal mechanics of convolutional neural networks within microbiological domains to determine the precise Raman spectral bands driving successful classification.
Journal of Trustworthy and Explainable Intelligent Systems
Original Research | Open access | 15 September 2024 | Article: 57